Endocrine Abstracts

Aim: In this study, we aimed to detect the serum Ghr levels in hypo and hyperthyroid patients at the time of diagnosis and after treatment in comparison with an age-, and sex-matched control group.Materials and methods: Thirty-two hypothyroid, 19 hyperthyroid and 30 control subjects were included in the study. Basal levels of serum free T3, free T4, TSH, anti-thyroid peroxidase (anti-TPO), anti Tg antibodies were measured by commercially available kits i...

Propylthiouracil (PTU), used to treat thyroid dysfunctions such as Graves’ disease, rarely induces lupus-like syndrome. A 52-year-old woman developed dermatological findings of systemic lupus erythematosus with malar rash, photosensitivity and discoid lupus erythematosus-like lesions, after 3 weeks of exposure to the drug. ANA and anti-dsDNA were positive. Skin biopsy of face revealed vacuolar changes in basal layer and lymphoid infiltration in perivascular region of derm...

Introduction: Wolfram syndrome has characterized by central diabetes insipidus (DI), diabetes mellitus (DM), optic atrophy (OA) and deafness. In this report we presented a Wolfram syndrome with hypergonadotropic hypogonadism.Case: A 18-year-old girl who has diabetes for 6 years was hospitalized due to blood sugar irregularity. Her medical history revealed frequent urination and enuresis for 2–3 years and primary amenorrhea. Furthermore she had hear ...

Aim: The present study was designed to examine the relationship between adiponectin gene (T45G in exon 2) polymorphism and clinical and hormonal characteristics in women with polycystic ovary syndrome (PCOS).Materials and methods: Ninety-six patients with PCOS and 93 healthy subjects were included in the study. Serum levels of sex steroids, insulin and adiponectin levels were measured. Insulin resistance was evaluated by homeostasis model assessment (HOM...

Aim: In this study, we aimed to assess psychiatric symptoms in 1000 type 2 diabetes mellitus (T2DM) patients.Material and methods: 297 patients (mean age 52.13±9.37 years, 190 women and 107 men) who had T2DM were included as a preliminary in this study. The presence of cheiroarthropathy, Dupuytren’s contracture, tinnel sign, and tendinitis was assessed. Diabetic retinopathy was assessed by direct ophthalmoscopy. Urinary albumin excretion was de...

Non adherence to medication schedules by patients with chronic illnesses has long been recognized as a problem. The aim of this study is to evaluate levothyroxine (L-T4) compliance, daily dosage and TSH levels under treatment in primary hypothyroid patients.We included 1636 primary hypothyroid patients over 1 year under L-T4 (F/M: 1469/167, 46±13 years of age) included from 11 tertiary health care ...